SCGhosh lab
Group news
&
Update
25-Dec-2023
Congratulations Dinesh and other member for your recent publication in J. Org. Chem
Palladium-Catalyzed Chelation-Assisted Aldehyde C−H Bond Activation of Quinoline-8-carbaldehydes: Synthesis of Amides from Aldehydes with Anilines and Other Amines
Dinesh Gopichand Thakur, Nileshkumar B. Rathod, Sachinkumar D. Patel, Dharmik M. Patel, Raj N. Patel, Mahesh A. Sonawane, and Subhash Chandra Ghosh
J. Org. Chem 2024 doi.org/10.1021/acs.joc.3c02139
In this article we have demonstrated a palladium-catalyzed methodology for the direct coupling of quinoline-8-carboxaldehyde with aryl iodide and/or aryl diazonium salt to synthesize 8-aryloylquinoline. Reverse reactivity was observed by changing the arylating source; electron-donating group-substituted aryl iodide favors the reaction and provided a very good yield of the desired ketone, whereas electron-withdrawing group-substituted aryl diazonium salt provided a better yield
Ph.D. Positions Available
Looking for bright and motivated students who wish to pursue their Ph.D. in the areas of Synthetic Organic Chemistry and Catalysis. Interested student, M.Sc. in Organic Chemistry can apply.
Post-Doctoral Positions Available
Ph.D. candidates who want to apply for own funding (e.g. CSIR-Nehru Post-Doctoral Fellowship, DST National Post Doctoral Fellowship , DST Women Scientists Scheme) are encouraged to contact. To apply, please submit your CV and research summary.
15- June- 2022
We warmly welcome Sachin Patel to our research group (UGC-JRF)
04-May-2022
Congratulations! Dr. Chiranjit Sen, recipient of AcSIR Best Ph.D. Thesis Award-2020 in Chemical Sciences
20-Sep. 2021
Congratulation Dr. Tapan Sahoo for successfully defending your thesis
8-Sep- 2021
Congratulations Tapan and the team for your recent publication in Tetrahedron Letters
Copper/Manganese Oxide Catalyzed Regioselective Amination of Quinoline N-Oxides: An Example of Synergistic Cooperative Catalysis
In this article we present a simple Cu-MnO heterogeneous catalyst for the synthesis of 2-amino quinoline via direct C-H amination of quinoline oxides with an amine under air, the most benign oxidant. The key advantages such as the reusability of the catalyst several times, the reaction is a ligand, base and, additive-free, and carried out under aerobic conditions.
26- Aug- 2021
We warmly welcome Nilesh Rathod to our research group (UGC-JRF)
09- Aug- 2021
Congratulations Souvik and the team for your recent publication in Chem Comm
Copper(II) mediated ortho C–H alkoxylation of aromatic amines
In this article we present an unprecedented hindered alkoxylation of picolinamide attached aromatic amines using economic copper salt and organic peroxide to get highly desirable α-tertiary alkyl aryl ethers. Synthesis of hindered alkyl aryl ether derivatives (R-O-Ar) remains a huge challenge and highly desirable in organic and medicinal chemistry because extensive substitution on the ether bond prevents the undesired metabolic process and thus avoids rapid degradation in vivo.
21- June- 2021
We warmly welcome Dharmik Patel to our research group (UGC-JRF)
22- Jan. 2021
Congratulation Harsh and the team for publishing your work on C-H Amidation and Amination of Arenes and Heteroarenes with Amide and Amine using Cu-MnO as a Reusable Catalyst in The Journal of Organic Chemistry